For adult patients with anxiety disorders, the FDA-approved maximum daily dose of diazepam is 40 mg per day, administered as 2-10 mg taken 2 to 4 times daily, though most patients respond adequately to lower doses of 4-40 mg daily. 1 Detailed Diazepam dosage information for adults, the elderly and children. Includes dosages for Anxiety, Muscle Spasm, Seizures and more; plus renal, liver and dialysis adjustments. In patients already receiving an opioid analgesic, prescribe a lower initial dose of Valium than indicated in the absence of an opioid and titrate based on clinical response. The maximum daily dose of oral diazepam (Valium) is 40 mg per day for adults, though this should be limited to the smallest effective amount, particularly in elderly patients. 1 Diazepam is used to treat anxiety, symptoms of acute alcohol withdrawal, and more. Find out what the recommended dosages are, how to take the drug, and more. Second dose: When required, may be administered after at least 4 hr after initial dose; if the second dose is administered, use a new blister pack of diazepam intranasal Detailed dosage guidelines and administration information for Valium (diazepam). Includes dose adjustments, warnings and precautions. Learn more about diazepam dosage, including available strengths, form, and how it's taken. Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm. Diazepam is available in several oral dosage forms, including a tablet, solution, and concentrated oral solution (Diazepam Intensol). The typical diazepam dosage for adults ranges from 2 mg to 10 mg by mouth 2 to 4 times per day. Lower dosages are recommended for children and older adults.